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Abstract #4610

Eliminating susceptibility induced hyperintensities in ultra highd field T1w MPRAGE brain images

Ruoyun Emily Ma1, Thomas Henry2, and Pierre-Fran├žois Van de Moortele1

1Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, 2Department of Neurology, University of Minnesota, Minneapolis, MN, United States

Ultra high field brain MPRAGE images are commonly affected by local susceptibility induced hyperintensities, which are pronounced in inferior frontal lobe and inferior temporal lobe. In this work, we propose a straightforward approach by applying a frequency offset of 300Hz and widening the bandwidth by 40% to the hyperbolic secant inversion pulse provided by the standard MPRAGE sequence, to eliminate this artefact without introducing additional incomplete inversion through the brain. This approach was tested across different subjects and proven to have robust performance in artefact elimination against variable local frequency offsets.

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