The sensitivity of T1 mapping towards brain maturation during the first years of life was shown in previous studies. This work investigates whether this sensitivity is high enough that age of young subjects can be directly estimate from T1 relaxometry, which in turn enables to determine the developmental stage of the subject’s brain. A random forest regression was employed to estimate subjects’ age based on median T1 values of different brain regions. Good correlation (r=0.95) was found between actual and predicted ages, and proof-of-concept results in a patient showed the potential of the proposed framework to detect developmental delays.
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