Magnetic resonance-guided focused ultrasound (MRgFUS) has many potential neurological applications, but skull-induced aberrations of the acoustic pressure field limit its specificity and safety. MR-acoustic radiation force imaging (MR-ARFI)-based methods have been proposed to refocus the pressure field in situ. However, they take too long for practical in vivo use. We propose a multi-voxel MR-ARFI-based autofocusing method for rapid aberration correction of MRgFUS acoustic pressure fields. We compare our proposed method to the canonical single-voxel MR-ARFI-based refocusing method and demonstrate that as few as two MR-ARFI acquisitions can be used to refocus a programmatically aberrated pressure field.
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