Abstract #0159

High-Resolution QSM for Simultaneous QSM/MRSI

Rong Guo^1,2, Yudu Li^1,2, Yibo Zhao^1,2, Tianyao Wang³, Yao Li^4,5, Brad Sutton^1,2,6, and Zhi-Pei Liang^1,2

¹Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States, ²Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, United States, ³Radiology Department, The Fifth People's Hospital of Shanghai, Shanghai, China, ⁴School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China, ⁵Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China, ⁶Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States

In this work, we present a new method to achieve high-resolution QSM for simultaneous QSM/MRSI experiments. This work extends SPICE with a novel data acquisition scheme that provides larger k-space coverage for the unsuppressed water signals. A union-of-subspaces model incorporating sensitivity encodings (parallel imaging) and pre-determined spatiospectral features is used to solve the underlying image reconstruction problem. High-resolution capability (on the order of 1.0 × 1.0 × 1.2 mm³) for QSM has been demonstrated in 3D in vivo simultaneous QSM/MRSI experiments.

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