Abstract #0365

Intra-session and inter-subject variability of 3D-FID-MRSI using single-echo volumetric EPI navigators at 3T

Philipp Moser¹, Korbinian Eckstein¹, Lukas Hingerl¹, Michael Weber¹, Stanislav Motyka¹, Bernhard Strasser^1,2, Andre van der Kouwe³, Simon Robinson¹, Siegfried Trattnig^1,4, and Wolfgang Bogner¹

¹High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, ²Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Vienna, MA, United States, ³Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology,, Harvard Medical School, Massachusetts General Hospital, Boston, MA, United States, ⁴Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria

We demonstrate the combination of 3D free induction decay proton MR spectroscopic imaging and spatial encoding via concentric-ring trajectories at 3T. To improve the reliability a well as the temporal stability, single-echo, imaging-based volumetric navigators for real-time motion/shim-correction were additionally integrated. All intra-subject coefficients of variation and most of the inter-subject coefficients of variation obtained with motion/shim-correction were lower (i.e., better) than without and resulted in higher SNRs and lower CRLBs.

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