Abstract #0486

Respiratory motion compensation for human cardiac 23Na MRI

Johanna Lott^1,2, Armin M. Nagel^1,3,4, Sebastian C. Niesporek¹, Thoralf Niendorf^5,6, Peter Bachert^1,2, Mark E. Ladd^1,2,7, and Tanja Platt¹

¹Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, ²Faculty of Physics and Astronomy, University of Heidelberg, Heidelberg, Germany, ³Institute of Radiology, University Hospital Erlangen, Erlangen, Germany, ⁴Institute of Medical Physics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, ⁵Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrueck Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany, ⁶MRI. TOOLS GmbH, Berlin, Germany, ⁷Faculty of Medicine, University of Heidelberg, Heidelberg, Germany

Sodium (²³Na) ion distribution plays a fundamental role in biological processes, in particular in myocardial function. ²³Na MRI provides noninvasive information about the total tissue sodium concentration. However, short relaxation times, low signal-to-noise ratio, breathing and heart motion render quantitative cardiac ²³Na MRI challenging and result in long acquisition times. We present a method to compensate for respiratory motion in ²³Na MRI by adding a linear phase in k-space with the goal to determine myocardial tissue sodium concentration. This enables a reduced measurement time for quantitative cardiac ²³Na MRI compared to retrospective sorting into one respiratory state.

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