It is reported that dynamic contrast imaging and T2 relaxation time can be used to differentiate benign and malignant breast lesions. However, few researches have investigated T1 and T2 relaxation time changes before and after contrast injection. But it's important for the diagnosis of breast diseases. Thus, the study aims to utilize the T1 and T2mapping in synthetic MR to differentiate benign and malignant lesions. Our results demonstrated that T1 and T2 mapping could constitute a new adjunct in the MRI diagnosis of breast diseases.