“Focal” epilepsy is a network aberration. Network characteristics in focal epilepsy due to calcified Neurocysticercal granuloma have not been elucidated. Forty-two patients of focal epilepsy with MRI evidence of either calcified granuloma, malformation of cortical development, mesial temporal sclerosis, or no imaging abnormality were included. Group-level Cortical thickness covariance networks were generated and compared. Focal epilepsy patients (including those with calcific granuloma) had significantly reduced network global efficiency and higher nodal characteristic path length/ Clustering coefficient/ Nodal local efficiency (p<0.05). Networks in focal epilepsy (“ including those due to calcific granuloma”) have higher segregation and lesser integration.
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