Youzhen Feng1, Zhongyuan Cheng1, Xiaoqiao Chen2, Xiaoqing Xiong1, Qiting Lin1, Dingkun SiTu1, Long Qian3, Huomei Chen1, and Xiangran Cai1
1Medical Imaging Center, First Affiliated Hospital, Jinan University, Guangzhou, Guangdong, China, Guangzhou, China, 2Medical Imaging Center, The Eighth Hospital of Sun Yat-sen University，shenzhen，China., Shenzhen, China, 3MR Research, GE Healthcare., Beijing, China
kurtosis imaging (DKI) is an advanced diffusion model and could identify the
heterogeneity of cellularity and microstructural complexity1,2. To
test whether the DKI could detect the functional changes of kidney in early Diabetic
kidney disease (DKD), the STZ-induced diabetic rats were applied in current
study. Further, the biochemical and pathological evidences would also be provided
to compare with the DKI biomarker.