Abstract #0974

Simultaneous distortion and motion correction in abdominal DW-MRI using dual echo EPI and slice-to-volume registration

Jaume Coll-Font^1,2, Onur Afacan^1,2, Scott Hoge^2,3, Bahram Marami⁴, Ali Gholipour^1,2, Jeanne Chow^1,2, Simon Warfield^1,2, and Sila Kurugol^1,2

¹Radiology, Boston Children's Hospital, Boston, MA, United States, ²Harvard Medical School, Boston, MA, United States, ³Radiology, Brigham and Women's Hospital, Boston, MA, United States, ⁴Icahn School of Medicine at Mount Sinai, New York, NY, United States

Diffusion-weighted MRI (DW-MRI) has been increasingly used in abdominal applications. However, unavoidable respiratory motion, as well as B0 field inhomogeneities reduce the accuracy of the quantitative parameters and hinders clinical applicability. In this work, we present a dual echo EPI DW-MRI and slice-to-volume registration method to jointly correct for geometric distortion and motion of the kidneys. The results show that our method effectively reduced geometric distortions, improved alignment of the DW-MR volumes and increased the precision of the estimated quantitative parameters.

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