We investigate the spatial specificity of sub-millimeter (0.8mm) single-shot spiral fMRI, and its feasibility for functional phase contrast. Scrutinizing activation patterns of a visual paradigm in 6 subjects, we find that significant contrast changes occur between adjacent voxels, contributing to the evidence of spatial specificity of spiral acquisition as well as gradient echo BOLD contrast, and its possible applications in laminar or columnar fMRI. Furthermore, the vessel-localized nature of the phase activation suggests its suitability for masking macrovascular confound effects.
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