Abstract #1238

Combined Working Memory and Attention Training Improves Cognition via Task-Specific and Transfer Effects

Daisuke Sawamura^1,2, Ryusuke Suzuki³, Keita Ogawa⁴, Shinya Sakai², Xinnan Li¹, Hiroyuki Hamaguchi¹, and Khin Khin Tha^5,6

¹Department of Biomarker Imaging Science, Graduate School of Biomedical Science and Engineering, Hokkaido University, Sapporo, Japan, ²Department of Functioning and Disability, Faculty of Health Sciences, Hokkaido University, Sapporo, Japan, ³Departments of Medical Physics, Hokkaido University Hospital, Sapporo, Japan, ⁴Department of Rehabilitation, Hokkaido University Hospital, Sapporo, Japan, ⁵Department of Diagnostic and Interventional Radiology, Hokkaido University, Sapporo, Japan, ⁶Global Station for Quantum Medical Science and Engineering, Hokkaido University, Sapporo, Japan

Little is known about how neurocognition is modulated upon combined computerized cognitive training (CCT). We developed a combined CCT program designed to improve several cognitive functions simultaneously, and evaluated its effect on neurocognitive performance and functional connectivity (FC) of the brain. The results suggest that the CCT improves not only the targeted functions but also the other aspects of neurocognition via augmentation of transfer effect. The LPFC and fronto-parieto-occipital networks are thought to play role.

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