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Abstract #1679

Mesoscopic imaging of perivascular spaces at 7T

Farshid Sepehrband1, Samantha Ma2, Jeiran Choupan2, Sook-Lei Liew2, and Arthur W Toga2
1Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, USC, Los Angeles, CA, United States, 2USC, Los Angeles, CA, United States

Imaging of the perivascular spaces (PVS) is of growing interest, especially due to its involvement in brain clearance and blood-brain barrier exchange [1]–[3]. PVS mapping is often limited to macroscopic PVS (>1mm), which limits the study of subtle morphological PVS alteration that is expected to occur in submillimeter resolution. Here we show the advantage of ultra-high field imaging for detailed quantification of PVS in vivoand noninvasively.

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