It is thought that hypercellular regions of glioma have lower ADC values via a restriction in flow path, but there is no consensus regarding the correlation between ADC values and the cellularity of histological biopsies. In this study a slightly stronger negative correlation was observed between sample cellularity and the average ADC across the biopsy region as compared to the average ADC across the whole tumour in patients with glioma. However, neither correlation was found to be significant, which could be due to a small cohort size and the variation in tumour biological factors other than cellularity affecting ADC.
This abstract and the presentation materials are available to members only; a login is required.