Abstract #1788

Penumbra Quantification from SWI visible Prominent Veins and its comparison with ASL-derived penumbra in patients with acute stroke

Rupsa Bhattacharjee^1,2, Rakesh Kumar Gupta³, Vijay Kant Dixit⁴, Praveen Gupta⁵, and Anup Singh^1,6

¹Center for Biomedical Engineering, Indian Institute of Technology Delhi, New Delhi, India, ²Philips Health Systems, Philips India Limited, Gurugram, India, ³Department of Radiology, Fortis Memorial Research Institute, Gurugram, India, ⁴Department of Interventional Neuroradiology, Fortis Memorial research Institute, Gurugram, India, ⁵Department of Neurology, Fortis Memorial research Institute, Gurugram, India, ⁶Department of Biomedical Engineering, All India Institute of Medical Sciences, New Delhi, India

Objectives are to enhance the PHVS visibility in SWI, quantify stroke penumbra from it and calculate the mismatch ratio between PHVS(SWI) and DWI. For algorithm performance evaluation, 3D non-contrast pCASL as a gold standard was used to calculate true mismatch ratio with DWI. The proposed approach demonstrates high correlation between the two mismatch ratios, suggesting that PHVS and SWI based penumbra quantification has the potential to be used as an alternative for perfusion based methods. If mismatch ratio can accurately be produced from PHVS SWI, it could potentially reduce the scan time for acute stroke.

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