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Abstract #2016

Real-time phase contrast MRI measurements of coughing in patients with Chiari malformation

Rob Lloyd1,2, Iain Ball3, Marcus Stoodley4, and Lynne Bilston1,2
1Neuroscience Research Australia, Randwick, Australia, 2Prince of Wales Clinical School, University of New South Wales, Randwick, Australia, 3Philips Australia & New Zealand, North Ryde, Australia, 4Department of Clinical Medicine, Macquarie University, Macquarie Park, Australia

Cerebrospinal fluid (CSF) flow, as characterised by real-time PCMRI, may inform surgeons whether a patient with Chiari malformation may benefit from decompression surgery. 5 healthy controls and 7 Chiari patients with (N=4) and without (N=3) coughing headache underwent MRI scanning to measure CSF velocities while coughing. Results suggest that Chiari patients with coughing triggered headaches have increased CSF velocities at the foramen magnum during a cough compared with both controls and patients without headache. This may help understand the mechanisms of coughing triggered headaches and provide a useful indicator for clinicians.

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