Primary aldosteronism (PA) increases cardiovascular morbidity. In order to elucidate the early features of heart damage of PA, we used the cardiac MRI and T1 mapping technique to evaluate and compare cardiac function and myocardium changes in PA and essential hypertension (EH) patients. Our results found that the PA patients had higher native T1 than the EH group, while other functional parameters had no significant differences between two groups. The change of myocardium was earlier in PA patients than in EH patients, suggesting that it is mainly due to myocardial fibrosis induced by inappropriate secretion of aldosterone.
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