Flow Effects in AIF Measurements for Quantitative Myocardial Perfusion

We study the flow effects in AIF estimation for myocardial perfusion MRI. Simulations were performed and radially acquired datasets were retrospectively analyzed. We reconstruct images using different number of rays and estimated AIF from each reconstruction. The results show an increase in peak AIF values with a longer acquisition window. For acquisition window of 125ms and 187ms, we found an averaged 10.6% and 22.9% increase when compared with acquisition window of 62ms. A low acquisition window is preferred to acquire an accurate AIF for quantitative myocardial perfusion MRI.