Yuting Wang1, Yuncai Ran2, Ming Zhu3, Xiao Wu4, Ajay Malhotra4, Xiaowen Lei2, Feifei Zhang2, Xiao Wang2, Shanshan Xie2, Jian Zhou2, Jinxia Zhu5, Jingliang Cheng2, and Chengcheng Zhu6
1Department of Radiology, Sichuan Provincial People's Hospital, Chengdu, China, 2Department of Magnetic Resonance, The first Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 34. Interventional department, The first Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 4Yale School of Medicine and Yale University, New Haven, CT, United States, 5MR Collaboration, Siemens Healthcare Ltd., Beijing, China, 63. Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States
Middle cerebral artery plaque burden on high-resolution MR was significantly higher in recurrent stroke group than in the first-onset acute stroke and chronic stroke groups (p=0.002). Patients with acute stroke had higher enhancement ratio than patients with chronic stroke (p=0.014). After adjustment of clinical demographic factors, plaque burden was the only independent imaging feature associated with recurrent stroke (odds ratio=2.26, per 10% increase, 95% CI, 1.03-4.96, p=0.042). In conclusion, higher plaque burden of MCA on MR is independently associated with recurrent ischemic stroke. MR vessel wall imaging may provide unique information for risk stratification of stroke patients.