Abstract #2127

Quantitative 3D dynamic contrast‐enhanced of Atherosclerosis by using 3D Stack of Star with Golden-angle radial sparse parallel reconstruction

Seong-Eun Kim¹, Ye Tian², Matthew Alexander¹, Dennis L Parker¹, Gerald S Treiman ^3,4, Adam de Havenon⁵, and J Scott McNally¹

¹UCAIR, Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, United States, ²Department of Physics and Astronomy, University of Utah, Salt Lake City, UT, United States, ³Department of Surgery, University of Utah, Salt Lake City, UT, United States, ⁴VASLCHCS, Salt Lake City, UT, United States, ⁵Department of Neurology, University of Utah, Salt Lake City, UT, United States

Carotid plaque inflammation can be measured with dynamic contrast enhanced (DCE) MRI and is a marker for plaque instability. Increased vascularity, which is one sign of plaque inflammation, can be detected from kinetic analysis of DCE images However, the trade-off between spatial and temporal resolution limits assessment to a small number of slices and ~15 seconds per time frame. To overcome this limitation, we implemented a short-TR 3D T1w Stack of Stars (SoS) sequence to enable retrospective image formation with arbitrary numbers of radial views by using Golden-angle radial sparse parallel (GRASP) reconstruction.

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