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Abstract #2213

Intra-cardiac flow kinetic energy assessment from 4D flow CMR imaging in pediatric and adult repaired Tetralogy of Fallot

XIAODAN ZHAO1, LIWEI HU2, RONG ZHEN OUYANG2, RU SAN TAN1,3, PING CHAI4, MARIELLE FORTIER3,5, SHUO ZHANG6, WEN RUAN1, SHUANG LENG1, JUN-MEI ZHANG1,3, BRYANT JENNIFER1, LYNETTE LS TEO4, ROB VAN DER GEEST7, TENG HONG TAN3,5, JAMES YIP4, JU LE TAN1,3, YUMIN ZHONG2, and LIANG ZHONG1,3
1National Heart Centre Singapore, Singapore, Singapore, 2Shanghai Children’s Medical Centre, Shanghai Jiaotong University School of Medicine, ShangHai, China, 3Duke-NUS Medical School, Singapore, Singapore, 4National University Hospital Singapore, Singapore, Singapore, 5KK Women’s and Children’s Hospital, Singapore, Singapore, 6Philips Germany, Humburg, Germany, 7Department of Radiology, Leiden University Medical Center, Leiden, Netherlands

Whole-heart 4D cardiovascular magnetic resonance (CMR) phase-contrast flow measurement enables qualitative and quantitative assessment of intra-cardiac flow. Its feasibility was investigated in 12 pediatric and 13 adult patients with repaired Tetralogy of Fallot (rTOF). Left ventricular (LV) kinetic energy (KE) and pathline-derived flow components were analyzed. KE parameters were significantly correlated with age, but only LV systolic KE remained significantly different after indexing to LV end-diastolic volume. Pediatric rTOF patients had similar LV ejection fraction, indexed LV volumes and mass, but significantly reduced indexed LV systolic KE, retained inflow and increased delayed ejection flow compared with adults.

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