Carotid atherosclerosis is a degenerative disease of the arterial wall, which can result in predisposition to cerebral thrombo-embolic stroke1. The combination of DANTE and VF-RARE (DANTE-VF-RARE) can suppress flow signal effectively. It was used for vessel wall imaging of human in the previous studies4. However, the feasibility of DANTE-VF-RARE sequence remains unclear for imaging of carotid for apoE-/- mouse. This work aims to develop 3D DANTE-VF-RARE on 7Tesla (T) and investigate its feasibility for vessel wall imaging of apoE-/- mouse.