Main challenge associated with conventional DCE-MRI of breast is compromise between spatial and temporal-resolution. In this study our objective is to develop an ultra-fast breast dynamic protocol keeping both spatial and temporal resolution sufficiently high. This is enabled by using compressed SENSE acceleration technique. Proposed Compressed-SENSE enabled ultra-fast dynamic breast DCE protocol design has the potential to be used as alternative of conventional DCE protocol. It gives contrast wash-in information from arteries and veins within very short time, and can significantly differentiate between malignant and benign breast lesions quantitatively (validated on proven 10 malignant and 10 benign cases).