We propose a sequence to simultaneously acquire apparent diffusion coefficient (ADC) and T2 values for detecting prostate cancer. ADC and T2 values of prostate cancer can simultaneously be acquired using not only a diffusion-weighted image, but also multiple echo time (TE) images without motion-probing gradient using echo-planar imaging (EPI). Moreover, the quantitative ADC and T2 maps can be produced in approximately 5 min. Combining ADC and T2 values was effective in differentiating between prostate cancer and the normal peripheral zone. Our rapid quantification imaging technique improves the accuracy of the diagnosis of prostate cancer.