The characteristics of liver cirrhosis are usually hepatic dysfunction and portal hypertension. Portal hypertension further leads to ascites and esophageal varices (EV). To our knowledge, no methods are currently available for the simultaneous evaluation of portal hypertension and EV severity. The results of this study positively illustrate that Gd-BOPTA-enhanced MRI can serve as a novel and efficient tool to simultaneously and accurately evaluate portal hypertension and high-risk EVs. Relative enhancement ratio (RE) is correlated with estimated HVPG. The formula (-6.483+15.612*portal vein width + 2.251 * RE - 0.176 * platelet count) could be used for the prediction of high-risk EVs.