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Abstract #2800

High Angular Resolution Diffusion Imaging (HARDI) in Meniscus

Nian Wang1, Gary Cofer1, Louis E. DeFrate2, Abigail Holt2, Amy L. McNulty2, Yi Qi1, Charles E. Spritzer1, and G. Allan Johnson1
1Department of Radiology, Duke University, Durham, NC, United States, 2Department of Orthopaedic Surgery, Duke University, Durham, NC, United States

Application of diffusion magnetic resonance imaging (dMRI) to map the complex collagen fibril structures of meniscus is still challenging, due to the short T2/T2* values, low fractional anisotropy (FA) values, and relatively low signal-to-noise (SNR). In this study, we imaged the porcine menisci in a preclinical 7 T system with relatively short echo time (TE ~ 11 ms). A 3D diffusion-weighted spin-echo pulse sequence was used for whole meniscus tractography at 125 ┬Ám isotropic resolution.

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