Abstract #2817

A three compartment complex signal model to describe the signal decay of ultrashort T2* tissues applied to ex vivo ovine Achilles tendons

Marta Brigid Maggioni¹, Martin Krämer¹, and Jürgen R. Reichenbach^1,2,3,4

¹Medical Physics Group, Institute of Diagnostic and Interventional Radiology, Jena University Hospital - Friedrich Schiller University, Jena, Germany, ²Michael Stifel Center for Data-driven and Simulation Science Jena, Friedrich Schiller University, Jena, Germany, ³Abbe School of Photonics, Friedrich Schiller University, Jena, Germany, ⁴Center of Medical Optics and Photonics, Friedrich Schiller University, Jena, Germany

Tendons are highly ordered tissues, mainly composed of collagen, and characterized by very short transverse T₂^* relaxation times. Even when using ultra-short echo-time imaging sequences, quantification of T₂^* is challenging as the origin and characteristics of the signal decay in tendons is still under debate. In this work, we finely sampled the decay of the transverse magnetization using an echo-train shifted multi-echo ultra-short echo-time sequence with 55 echoes and applied a complex tri-exponential model to extract T₂^* constants.

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