We present a method for bilateral sodium magnetic resonance imaging (MRI) of the lower extremities. Sodium MRI can provide direct information on tissue biochemistry not available through standard proton MRI, and could therefore potentially assist in disease diagnosis. Our preliminary results demonstrate the application of large field-of-view sodium MRI to the musculoskeletal system for potential compositional assessment of multiple tissues in both legs including muscle, cartilage, synovium and arteries.
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