TFIR is a novel regularization framework for total field quantitative susceptibility mapping. This method employs spatial frequency selection and R2* information within the L2 regularization method to map field to susceptibility source. It outperforms local field methods and existing regularization frameworks for total field susceptibility mapping, such as LN-QSM when computing error with respect to COSMOS and numerical and gadolinium phantoms. Hemorrhage cases and non-hemorrhage in vivo cases have reduced streaking and shadowing artifacts when reconstructed using TFIR compared to PDF-MEDI-SMV and LN-QSM. Future directions include spatial frequency selection automation in order to produce optimal signal to noise and accuracy.