Abstract #3285

Separating spin-compartment in arterial spin labeling using delays alternating with nutation for tailored excitation (DANTE) pulse

Shota Ishida¹, Hirohiko Kimura², Naoyuki Takei³, Yasuhiro Fujiwara⁴, Tsuyoshi Matsuda⁵, Yuki Matta¹, Masayuki Kanamoto¹, Nobuyuki Kosaka², and Eiji Kidoya¹

¹Radiological center, University of Fukui Hospital, Eiheiji, Japan, ²Department of Radiology, Faculty of Medical Sciences, University of Fukui, Eiheiji, Japan, ³Global MR Applications and Workflow, GE Healthcare Japan, Hino, Japan, ⁴Department of Medical Image Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan, ⁵Division of Ultra-high Field MRI, Institute for Biomedical Science, Iwate Medical University, Shiwa-gun, Japan

Delays alternating with nutation for tailored excitation (DANTE) pulse is capable of uniform and flow velocity related signal suppression. DANTE-ASL was compared to T₂-mesurement in ASL (T₂-ASL) to validate what spin-compartment is suppressed by DANTE. T₂-ASL showed labeled signal remained in vascular compartment even at a PLD of 2.0 s. However, ASL signals using DANTE were approximately similar value in all the PLDs (0.5, 1.0, 2.0, and 3.0 s), because ASL signals in vascular compartment were suppressed selectively and sufficiently with concurrently preserving signals in tissue compartment. We could eliminate vascular compartment from total ASL signal using DANTE.

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