In this work, we applied single-shot steady-state MR elastography with spiral readout for quantifying shear wave speed (SWS) from endogenous pulsation to 40 Hz external vibrations with high sampling rate for first-time measurement of SWS dispersion of in vivo human brain in the ultra-low frequency regime. Ground truth SWS was determined by profile fitting approaches and reproduced by SWS mapping based on frequency-adaptive multi-component wave-number inversion. The obtained SWS dispersion was fitted by two-parameter viscoelastic models showing that brain tissue is dominated by fluid properties in this ultra-low frequency regime. Our method is potentially sensitive to vessel-related neurological disorders.
This abstract and the presentation materials are available to members only; a login is required.