Major MRI scanner upgrades are generally required to improve performance and image quality; however, they can also potentially introduce systematic changes in quantitative MRI (qMRI) metrics and affect their accuracy and precision. To date the evaluation of the effect of scanner upgrades has focussed mainly on volumetric measurements, whereas the effect on quantitative parametric maps remains unexplored, especially when comparing analog and digital signal pathways plus multiband. Here we report findings on quantitative T1 to assess the potential effect of scanner upgrades on qMRI. We found negligible differences, suggesting that T1 measurements remain stable following a major scanner upgrade.
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