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Abstract #3778

Cross vendor validation of Hybrid Multidimensional MRI in the non-invasive measurement of prostate tissue composition

Aritrick Chatterjee1, Grace Lee2, Deb Dietz2, Aytekin Oto1, and Gregory Karczmar1
1Department of Radiology, University of Chicago, Chicago, IL, United States, 2Ingalls Memorial Hospital, Flossmoor, IL, United States

This study evaluates the consistency of HM-MRI for non-invasive measurement of prostate tissue composition on scanners from two MRI vendors. HM-MRI was performed on Philips Achieva 3T (with endorectal coil) and Siemens Skyra 3T (without endorectal coil) MRI scanners. HM-MRI metrics measured for cancerous and benign prostatic tissue using Philips and Siemens were similar, with slight variation due to different patients in each cohort. Diagnostic accuracy for detecting PCa using HM-MRI was similar for both MR vendors: Philips (AUC = 0.94-0.99, p<0.05) and Siemens (AUC = 0.83-0.98, p<0.05).

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