Meeting Banner
Abstract #3887

To smooth or not to smooth? Modelling the impact of spatially correlated physiological noise in fMRI

Nad├Ęge Corbin1, Oliver Josephs1, and Martina F Callaghan1
1Wellcome Centre for Human Neuroimaging, UCL Institute of Neurology, London, United Kingdom

Spatial smoothing is common in fMRI analyses but the benefit to functional sensitivity can vary depending on baseline signal-to-noise, inherent smoothness and physiological noise characteristics. Here we propose an extended model that can quantify each of these properties in addition to parameterising the degree of spatial correlation in the physiological noise. The model is validated through simulation and in vivo experiment. This new model allows the complete characterisation of the impact of spatial smoothing from a single fMRI time series enabling researchers to efficiently gain insight into their data and to optimise processing pipelines.

This abstract and the presentation materials are available to members only; a login is required.

Join Here