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Abstract #3903

Compensatory Effect of Thalamus on Numerical Stroop Task in Senior Adults

Chu-Shin Peng1, Shang-Cheng Chiu2, Fan-Chi Hsiao2, Chih-Mao Huang3, Chi-Yun Liu1, Chien-Ming Yang2, and Changwei Wesley Wu4
1Taipei Medical University, Taipei, Taiwan, 2Department of Psychology, National Chengchi University, Taipei, Taiwan, 3National Chiao Tung University, Hsinchu, Taiwan, 4Graduate Institute of Mind, Brain and Consciousness, Taipei Medical University, Taipei, Taiwan

To unveil the time-of-day effect in the aging process, we recruited both young and senior adults to participate fMRI experiments with the numerical Stroop task before and after nap. Beyond the dorsal attention network, we found the thalamus activity showed facilitating effect in the senior adults but the opposite way in the young adults. Such finding supports the compensation-related utilization of neural circuits hypothesis across age groups, but the time-of-day effect was relatively minor compared to the age effect.

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