7.0T MRI provides precise visualization and targeting of brain structures for image-guided stereotactic neurosurgery. However, image localizers used by stereotactic systems do not exist for 7.0T scanners. Challenges in their development include: the small bore creates geometric constraints that disallow use of conventional localizers, and the increased B0 increases geometric distortion, affecting registration accuracy. Here, a skull-contoured localizer utilizing point fiducials was designed to attach to a novel stereotactic frame. Extracranial distortion was thoroughly mapped using several optimized imaging sequences. This data was used to optimally place fiducials on the localizer, improving registration accuracy.
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