Meeting Banner
Abstract #4560

Intravoxel incoherent motion and diffusion kurtosis imaging in the assessment of pathological grades of clear cell renal cell carcinoma

Qing Xu1, Weiqiang Dou2, and Jing Ye1
1Department of Radiology, Clinical Medical School of Yangzhou University, Northern Jiangsu People’s Hospital, Yangzhou, 457, China, 2GE Healthcare, MR Research China, Beijing, China

In this study, we aimed to investigate whether intravoxel incoherent motion (IVIM) and diffusion kurtosis imaging (DKI) techniques can be used to evaluate the pathological grade of clear cell renal cell carcinoma (ccRCC) patients preoperatively. As a result, the IVIM-related parameters (ADC, apparent diffusion coefficient; D, true diffusivity) and DKI-related parameters (MD, mean diffusivity; MK, mean kurtosis) have shown significant differences between low- and high-grade ccRCC(0.58±0.11 vs 0.48±0.08, 1.39±1.18 vs 0.98±0.21, 2.12±0.35 vs 1.59±0.32, 0.53±0.13 vs 1.59±0.32; p<0.05). Therefore, IVIM and DKI techniques can be used effective tools to differentiate low- and high-grade ccRCC.

This abstract and the presentation materials are available to members only; a login is required.

Join Here