Cellular-interstitial water exchange rate is an important property of tumor, potentially associated with tumor aggressiveness and treatment response. It is not trivial to measure the water exchange rate, not to mention the challenges in measuring it at a high spatial resolution. In this study, we use the 3D-UTE-GRASP method1 to generate water exchange rate maps and compare them with those measured using diffusion time-dependent diffusion kurtosis imaging2.
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