Abstract #0096

In vivo human T2* imaging at 0.35 mm reveals up to 15 ms of local variations within gray matter across depths at 7T

Omer Faruk Gulban^1,2, Saskia Bollman³, Renzo Huber¹, Kendrick Kay⁴, Benedikt Poser¹, Federico De Martino¹, and Dimo Ivanov¹

¹Department of Cognitive Neuroscience , Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands, ²Brain Innovation, Maastricht, Netherlands, ³Centre for Advanced Imaging, The University of Queensland, Brisbane, Australia, ⁴Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States

We measured in vivo human brain T₂^* values using 7T MRI at 0.35 × 0.35 × 0.35 mm³. We simultaneously targeted calcarine sulcus and Heschl’s gyrus. Our results show that gray matter T₂^* varies up to 15 ms (global range being mostly in between 25-45 ms) from deep to superficial layers. The stria of Gennari shows up as a major reduction of T₂^* within calcarine sulcus. However, a similar layering is not visible within Heschl’s gyrus. B₀ alignment effects seem to be not as strong as the biological tissue composition effects that are observed across the visual and auditory regions.

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