We propose a novel methodology to identify spatio-temporal patterns of interictal epileptic activity in refractory epileptic patients using only BOLD functional MRI. It is based on clustering the activity-inducing signal deconvolved from the fMRI data with the Infomap algorithm. The proposed approach was validated on data acquired during a finger tapping task, and evaluated in four epileptic patients scanned at 7T. This method obtained activation maps that were concordant with the results obtained with EEG-informed GLM and MEG-based dipole source localization in 3 out of 4 patients, demonstrating its potential for mapping epileptic activity based only on fMRI data.
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