Even after a large number of studies with varying outcome, the effect of brain activation on the 31P spectrum is still unclear. Here, the SNR gain expected from a field strength of 9.4 T is used to determine changes in the metabolite peaks during a 5 min stimulus. In spite of the high SNR and spectral quality, no significant variations were found. Especially the amplitude and linewidth of the PCr-peak did not change, and, while the signal of extracellular inorganic phosphate was well visible after averaging over all subjects, no variations in its amplitude or position were observed.
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