Either peak E-fields on simple geometries with uniform interior properties as suggested by IEC or coupled E-field and neurodynamic simulations on realistic body models can be employed in PNS optimal gradient coil design. Magneto quasi-static simulations were performed to compare the magnitude and location of the peak E-fields in uniform interior body models with smoothed or realistic surface features to fully heterogeneous Virtual Family models. Although peak E-fields are higher on the heterogeneous body models due to complex tissue interfaces, simplified and/or homogeneous models represent a more practical and robust approach predicting population-wide PNS performance.
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