Abstract #2671
Ex vivo 7T MRI of resection specimen of oral cancer to improve margin control.
Klijs J. de Koning1, Rob Noorlag1, Annette van der Toorn2, Gerben E. Breimer3, Jan Willem Dankbaar4, Remco de Bree1, and Marielle E.P. Philippens5
1Head and Neck Surgical Oncology, University Medical Center Utrecht, Utrecht, Netherlands, 2Biomedical MR Imaging & Spectroscopy Group, University Medical Center Utrecht, Utrecht, Netherlands, 3Pathology, University Medical Center Utrecht, Utrecht, Netherlands, 4Radiology, University Medical Center Utrecht, Utrecht, Netherlands, 5Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands
Synopsis
We validated the measured resection margins of the surgical specimens of tongue carcinoma on 7T ex vivo MRI with histopathology using T2 weighted MRI. In 3D T2wTSE (250 μm3) with an acquisition time of 15-20 minutes, the resection margins was undestimated by 0.5 mm (+/- 1.3 mm). This will be developed into a clinical study with immediate re-resection during surgery to prevent adjuvant (chemo)radiotherapy, which is associated with radiation induced side effects.
This abstract and the presentation materials are available to members only;
a login is required.
Join Here
