Abstract #4385

Saturated Multi-delay Arterial Spin Labeling (SAMURAI) Technique for Simultaneous Perfusion and T1 Quantification of Kidneys

Zihan Ning¹, Shuo Chen¹, Zhensen Chen², Hualu Han¹, Huiyu Qiao¹, Rui Shen¹, Peng Wu³, and Xihai Zhao¹

¹Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine Tsinghua University, Beijing, China, ²Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China, ³Philips Healthcare, Shanghai, China

Synopsis

We proposed a Saturated Multi-delay Arterial Spin Labeling (SAMURAI) technique with a correspondingly modified kinetic model to achieve simultaneous acquisitions of RBF, aBAT, tBAT and T1 map in kidney with a single scan. SAMURAI provided T1 map with excellent correlation (R²=0.976) compared with IR-SE. Compared with multi-TI FAIR, SAMURAI provided equally reliable ASL and T1 quantification results (ICC: 0.875-0.958) with excellent scan-rescan repeatability (ICC: 0.905-0.992) and significantly reduced scan time (45’ vs 4’6’’ for 9 TIs).

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