The ascending aorta is poorly delineated on DWI due to the heartbeat, making it difficult to assess the activity of large vessel vasculitis using MRI. We investigated the utility of acceleration motion compensation diffusion-weighted imaging (aMC-DWI) compared with conventional DWI (cDWI) to detect active inflammation of the accenting aorta. The phantom experiment revealed that aMC-DWI showed a significantly higher median visual score than cDWI in both experimenters (P =.048 for both). The clinical study on 11 patients showed that aMC-DWI had higher sensitivity, specificity, and positive predictive value (with FDG-PET/CT as the reference method) than cDWI.
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