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Abstract #4861

Highly accelerated 4D flow MRI using compressed sensing in type B aortic dissection

Ozden Kilinc1, Stanley Chu1, Elizabeth K. Weiss1,2, Justin Baraboo1,2, Anthony Maroun1, Ning Jin3, Kelvin Chow1,4, Xiaoming Bi4, Rachel Davids4, Chris Mehta5, S. Chris Malaisrie5, Andrew Hoel6, Michael Markl1,2, and Bradley D. Allen1
1Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States, 2Department of Biomedical Engineering, Northwestern University, Chicago, IL, United States, 3Cardiovascular MR R&D, Siemens Medical Solutions USA, Inc., Cleveland, OH, United States, 4Cardiovascular MR R&D, Siemens Medical Solutions USA, Inc., Chicago, IL, United States, 5Division of Cardiac Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States, 6Division of Vascular Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States

Synopsis

4D flow MRI is an established quantitative MR imaging technique for evaluating complex blood flow patterns. However, clinical applications of standard 4D flow MRI technique is limited by long scan times associated with multidimensional imaging. Compressed sensing (CS) acceleration can significantly reduce scan time through dramatic data undersampling, but it is not clear how this undersampling impacts assessment of flow patterns in type B aortic dissection (TBAD). In this study, we investigate performance of highly accelerated CS 4D flow MRI at two different acceleration factor levels (R=7.7 and 10.2) to evaluate aortic flow dynamics in volunteers and patients with TBAD.

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