This talk will summarize several diagnostic applications of RT-MRI. Within cardiac imaging, I will show examples of left ventricular function, valvular flow, shortening exam time, and the very common setting of arrhythmia. Within joint motion imaging, I will show examples assessing instability in the wrist joint and temporomandibular joint. In the upper airway, I will show examples assessing airway anatomy and function during speech production and sleep-disordered breathing. Finally, I will provide some reflections on the opportunities and barriers for increased adoption of diagnostic RT-MRI.