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Abstract #7916

Data Acquired Using DCE-MRI are Unsuitable for Measuring Water Exchange

David L. Buckley1

1Division of Biomedical Imaging, University of Leeds, United Kingdom

DCE-MRI experiments are designed to measure tracer exchange. We can choose to make them sensitive to water exchange but in doing so we compromise their ability to measure tracer exchange, particularly their ability to measure the arterial input function (AIF). The choice is simple, EITHER measure tracer exchange parameters alone and well OR measure tracer exchange and water exchange parameters together but poorly.

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