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Abstract #8178

GlycoCEST, GlucoCEST, pH Agents, Translation to Humans

Xavier Golay1, Moritz Zaiss2, Steffi Thust3, and Mina Kim1

1Institute of Neurology, University College London, London, United Kingdom, 2Max Planck Institute for Biological Cybernetics, Tuebingen, Germany, 3Radiology, National Hospital for Neurology and Neurosurgery, London, United Kingdom

CEST is a powerful technique to measure metabolites and other molecules in small concentration through indirect exchange of its labile protons by saturation transfer. In this presentation, a review of its use to indirectly assess metabolic processes is presented, based on amide proton transfer imaging, as well as GlucoCEST and GlycoCEST.

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