MR Microscopy of Rat Hippocampal Slice Cultures: a Novel Model for Studying Cellular Processes and Chronic Perturbations to Tissue Microstructure
Shepherd T, Blackband S, Scheffler B, King M, Stanisz G, Steindler D
University of Florida
We report MRI microscopy of hippocampal slice cultures, which can be sustained viably for several weeks. This novel method should aid investigations of chronic tissue pathology, such as beta-amyloid plaque formation, and facilitate investigations that employ stem cell or molecular imaging techniques.